STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (145 aa)    
Predicted Functional Partners:
KCNH2
Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
     
 0.907
KCNE4
Potassium voltage-gated channel subfamily E regulatory subunit 4.
      
 0.893
KCNE1
Potassium voltage-gated channel subfamily E member 1.
      
 0.856
KCNJ8
Potassium voltage-gated channel subfamily J member 8.
      
 0.801
KCNQ1
Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.
    
 
 0.792
KCND3
Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family.
    
 
 0.785
KCNE3
Potassium voltage-gated channel subfamily E member 3 isoform X1.
      
 0.770
SCN2B
Sodium voltage-gated channel beta subunit 2.
      
 0.727
SCN3B
Sodium voltage-gated channel beta subunit 3.
   
  
 0.678
KCNJ2
Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...]
      
 0.676
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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