node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG16L2 | CSNK1G1 | ENSSSCP00000015737 | ENSSSCP00000051648 | Autophagy related 16 like 2. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.572 |
ATG16L2 | OAZ2 | ENSSSCP00000015737 | ENSSSCP00000036708 | Autophagy related 16 like 2. | Ornithine decarboxylase antizyme 2. | 0.676 |
ATG16L2 | PIF1 | ENSSSCP00000015737 | ENSSSCP00000038141 | Autophagy related 16 like 2. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.524 |
CCDC33 | CSNK1G1 | ENSSSCP00000002087 | ENSSSCP00000051648 | Coiled-coil domain containing 33. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.681 |
CNOT6 | CSNK1G1 | ENSSSCP00000063043 | ENSSSCP00000051648 | CCR4-NOT transcription complex subunit 6. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.528 |
CNOT6 | IMPA1 | ENSSSCP00000063043 | ENSSSCP00000027371 | CCR4-NOT transcription complex subunit 6. | Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates. | 0.577 |
CSNK1G1 | ATG16L2 | ENSSSCP00000051648 | ENSSSCP00000015737 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Autophagy related 16 like 2. | 0.572 |
CSNK1G1 | CCDC33 | ENSSSCP00000051648 | ENSSSCP00000002087 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Coiled-coil domain containing 33. | 0.681 |
CSNK1G1 | CNOT6 | ENSSSCP00000051648 | ENSSSCP00000063043 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | CCR4-NOT transcription complex subunit 6. | 0.528 |
CSNK1G1 | IMPA1 | ENSSSCP00000051648 | ENSSSCP00000027371 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates. | 0.548 |
CSNK1G1 | OAZ2 | ENSSSCP00000051648 | ENSSSCP00000036708 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Ornithine decarboxylase antizyme 2. | 0.669 |
CSNK1G1 | PIF1 | ENSSSCP00000051648 | ENSSSCP00000038141 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] | 0.587 |
CSNK1G1 | PPP1CA | ENSSSCP00000051648 | ENSSSCP00000032273 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.506 |
CSNK1G1 | PPP1R10 | ENSSSCP00000051648 | ENSSSCP00000030807 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | 0.526 |
CSNK1G1 | RUVBL1 | ENSSSCP00000051648 | ENSSSCP00000019846 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.553 |
CSNK1G1 | TMPRSS11E | ENSSSCP00000051648 | ENSSSCP00000042790 | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | Transmembrane protease serine; Belongs to the peptidase S1 family. | 0.514 |
IMPA1 | CNOT6 | ENSSSCP00000027371 | ENSSSCP00000063043 | Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates. | CCR4-NOT transcription complex subunit 6. | 0.577 |
IMPA1 | CSNK1G1 | ENSSSCP00000027371 | ENSSSCP00000051648 | Inositol monophosphatase 1; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.548 |
OAZ2 | ATG16L2 | ENSSSCP00000036708 | ENSSSCP00000015737 | Ornithine decarboxylase antizyme 2. | Autophagy related 16 like 2. | 0.676 |
OAZ2 | CSNK1G1 | ENSSSCP00000036708 | ENSSSCP00000051648 | Ornithine decarboxylase antizyme 2. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.669 |