STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF3PHD finger protein 3. (2032 aa)    
Predicted Functional Partners:
NIPBL
Nipped-B protein.
   
  
 0.907
PTP4A1
Protein tyrosine phosphatase type IVA 1 isoform X1.
 
    
 0.835
RPRD1A
Regulation of nuclear pre-mRNA domain containing 1A.
   
  
 0.786
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.781
VPS52
VPS52 subunit of GARP complex.
      
 0.755
MED12L
Mediator of RNA polymerase II transcription subunit 12-like protein isoform X5.
      
 0.743
NAT10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
      
 0.738
CHD9
Chromodomain helicase DNA binding protein 9.
   
 
 0.730
TINAG
Tubulointerstitial nephritis antigen; Belongs to the peptidase C1 family.
      
 0.724
PCF11
Pre-mRNA cleavage complex 2 protein Pcf11 isoform 1.
   
  
 0.712
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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