node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EPHX2 | NADSYN1 | ENSSSCP00000040448 | ENSSSCP00000063495 | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.523 |
EPHX2 | NT5E | ENSSSCP00000040448 | ENSSSCP00000030955 | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.875 |
EPHX2 | NUDT13 | ENSSSCP00000040448 | ENSSSCP00000052057 | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | Nudix hydrolase 13. | 0.811 |
GTF3C1 | IP6K2 | ENSSSCP00000008344 | ENSSSCP00000059430 | General transcription factor 3C polypeptide 1 isoform 1. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.652 |
GTF3C1 | NUDT13 | ENSSSCP00000008344 | ENSSSCP00000052057 | General transcription factor 3C polypeptide 1 isoform 1. | Nudix hydrolase 13. | 0.649 |
GTF3C1 | RCBTB1 | ENSSSCP00000008344 | ENSSSCP00000043804 | General transcription factor 3C polypeptide 1 isoform 1. | RCC1 and BTB domain containing protein 1. | 0.653 |
GTF3C1 | RSPRY1 | ENSSSCP00000008344 | ENSSSCP00000003039 | General transcription factor 3C polypeptide 1 isoform 1. | RING finger and SPRY domain-containing protein 1 isoform 1. | 0.671 |
GTF3C1 | TPRA1 | ENSSSCP00000008344 | ENSSSCP00000012386 | General transcription factor 3C polypeptide 1 isoform 1. | Transmembrane protein adipocyte associated 1. | 0.649 |
GTF3C1 | ZC3H15 | ENSSSCP00000008344 | ENSSSCP00000016981 | General transcription factor 3C polypeptide 1 isoform 1. | Zinc finger CCCH-type containing 15. | 0.645 |
IP6K2 | GTF3C1 | ENSSSCP00000059430 | ENSSSCP00000008344 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | General transcription factor 3C polypeptide 1 isoform 1. | 0.652 |
IP6K2 | NUDT13 | ENSSSCP00000059430 | ENSSSCP00000052057 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | Nudix hydrolase 13. | 0.652 |
IP6K2 | RCBTB1 | ENSSSCP00000059430 | ENSSSCP00000043804 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | RCC1 and BTB domain containing protein 1. | 0.660 |
IP6K2 | RSPRY1 | ENSSSCP00000059430 | ENSSSCP00000003039 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | RING finger and SPRY domain-containing protein 1 isoform 1. | 0.675 |
IP6K2 | TPRA1 | ENSSSCP00000059430 | ENSSSCP00000012386 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | Transmembrane protein adipocyte associated 1. | 0.654 |
IP6K2 | ZC3H15 | ENSSSCP00000059430 | ENSSSCP00000016981 | Kinase; Belongs to the inositol phosphokinase (IPK) family. | Zinc finger CCCH-type containing 15. | 0.647 |
NADSYN1 | EPHX2 | ENSSSCP00000063495 | ENSSSCP00000040448 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | 0.523 |
NADSYN1 | NT5E | ENSSSCP00000063495 | ENSSSCP00000030955 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.817 |
NADSYN1 | NUDT13 | ENSSSCP00000063495 | ENSSSCP00000052057 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nudix hydrolase 13. | 0.800 |
NT5E | EPHX2 | ENSSSCP00000030955 | ENSSSCP00000040448 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | 0.875 |
NT5E | NADSYN1 | ENSSSCP00000030955 | ENSSSCP00000063495 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.817 |