Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT3 | CDC42 | ENSSSCP00000071150 | ENSSSCP00000029815 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.484 |
| AKT3 | LOC100511937 | ENSSSCP00000071150 | ENSSSCP00000053353 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.941 |
| AKT3 | PIK3CB | ENSSSCP00000071150 | ENSSSCP00000052823 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. | 0.952 |
| AKT3 | PIK3R1 | ENSSSCP00000071150 | ENSSSCP00000024885 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.685 |
| AKT3 | PIK3R2 | ENSSSCP00000071150 | ENSSSCP00000060475 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.588 |
| AKT3 | PIK3R5 | ENSSSCP00000071150 | ENSSSCP00000033970 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphoinositide 3-kinase regulatory subunit 5; Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein- mediated activation of PIK3CG. | 0.926 |
| CDC42 | AKT3 | ENSSSCP00000029815 | ENSSSCP00000071150 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.484 |
| CDC42 | EGFR | ENSSSCP00000029815 | ENSSSCP00000068369 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Receptor protein-tyrosine kinase. | 0.853 |
| CDC42 | LOC100511937 | ENSSSCP00000029815 | ENSSSCP00000053353 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.927 |
| CDC42 | PIK3CB | ENSSSCP00000029815 | ENSSSCP00000052823 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. | 0.996 |
| CDC42 | PIK3R1 | ENSSSCP00000029815 | ENSSSCP00000024885 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Phosphoinositide-3-kinase regulatory subunit 1. | 0.690 |
| CDC42 | PIK3R2 | ENSSSCP00000029815 | ENSSSCP00000060475 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.619 |
| CDC42 | RAC2 | ENSSSCP00000029815 | ENSSSCP00000070230 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.931 |
| CDC42 | RAC3 | ENSSSCP00000029815 | ENSSSCP00000047362 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 3. | 0.929 |
| EGFR | CDC42 | ENSSSCP00000068369 | ENSSSCP00000029815 | Receptor protein-tyrosine kinase. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.853 |
| EGFR | LOC100511937 | ENSSSCP00000068369 | ENSSSCP00000053353 | Receptor protein-tyrosine kinase. | Uncharacterized protein. | 0.959 |
| EGFR | PDGFRA | ENSSSCP00000068369 | ENSSSCP00000048936 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.956 |
| EGFR | PIK3CB | ENSSSCP00000068369 | ENSSSCP00000052823 | Receptor protein-tyrosine kinase. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. | 0.948 |
| EGFR | PIK3R1 | ENSSSCP00000068369 | ENSSSCP00000024885 | Receptor protein-tyrosine kinase. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.909 |
| EGFR | PIK3R2 | ENSSSCP00000068369 | ENSSSCP00000060475 | Receptor protein-tyrosine kinase. | Uncharacterized protein. | 0.660 |
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