node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHODH | DPYD | ENSSSCP00000066486 | ENSSSCP00000007333 | Dihydroorotate dehydrogenase (quinone). | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.527 |
DHODH | FADS6 | ENSSSCP00000066486 | ENSSSCP00000018251 | Dihydroorotate dehydrogenase (quinone). | Fatty acid desaturase 6. | 0.803 |
DHODH | FDXR | ENSSSCP00000066486 | ENSSSCP00000046967 | Dihydroorotate dehydrogenase (quinone). | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.803 |
DHODH | KISS1 | ENSSSCP00000066486 | ENSSSCP00000056750 | Dihydroorotate dehydrogenase (quinone). | KiSS-1 metastasis-suppressor. | 0.900 |
DHODH | OXNAD1 | ENSSSCP00000066486 | ENSSSCP00000053413 | Dihydroorotate dehydrogenase (quinone). | Oxidoreductase NAD binding domain containing 1. | 0.877 |
DHODH | SDHA | ENSSSCP00000066486 | ENSSSCP00000026945 | Dihydroorotate dehydrogenase (quinone). | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.519 |
DHODH | UMPS | ENSSSCP00000066486 | ENSSSCP00000012636 | Dihydroorotate dehydrogenase (quinone). | Uridine monophosphate synthetase. | 0.998 |
DPYD | DHODH | ENSSSCP00000007333 | ENSSSCP00000066486 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone). | 0.527 |
DPYD | FADS6 | ENSSSCP00000007333 | ENSSSCP00000018251 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Fatty acid desaturase 6. | 0.803 |
DPYD | FDXR | ENSSSCP00000007333 | ENSSSCP00000046967 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.803 |
DPYD | KISS1 | ENSSSCP00000007333 | ENSSSCP00000056750 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | KiSS-1 metastasis-suppressor. | 0.900 |
DPYD | OXNAD1 | ENSSSCP00000007333 | ENSSSCP00000053413 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Oxidoreductase NAD binding domain containing 1. | 0.919 |
DPYD | SDHA | ENSSSCP00000007333 | ENSSSCP00000026945 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.519 |
DPYD | UMPS | ENSSSCP00000007333 | ENSSSCP00000012636 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine monophosphate synthetase. | 0.997 |
FADS6 | DHODH | ENSSSCP00000018251 | ENSSSCP00000066486 | Fatty acid desaturase 6. | Dihydroorotate dehydrogenase (quinone). | 0.803 |
FADS6 | DPYD | ENSSSCP00000018251 | ENSSSCP00000007333 | Fatty acid desaturase 6. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.803 |
FADS6 | OXNAD1 | ENSSSCP00000018251 | ENSSSCP00000053413 | Fatty acid desaturase 6. | Oxidoreductase NAD binding domain containing 1. | 0.644 |
FDXR | DHODH | ENSSSCP00000046967 | ENSSSCP00000066486 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Dihydroorotate dehydrogenase (quinone). | 0.803 |
FDXR | DPYD | ENSSSCP00000046967 | ENSSSCP00000007333 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.803 |
FDXR | IYD | ENSSSCP00000046967 | ENSSSCP00000058555 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine. Belongs to the nitroreductase family. | 0.588 |