STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP42Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1344 aa)    
Predicted Functional Partners:
DDIAS
DNA damage induced apoptosis suppressor.
      
 0.729
SPRTN
Uncharacterized protein.
      
 0.725
POC1A
POC1 centriolar protein A.
      
 0.611
SPATA24
Spermatogenesis-associated protein 24.
      
 0.611
MOV10L1
AAA_12 domain-containing protein.
      
 0.604
GOPC
PDZ domain-containing protein.
      
 0.553
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 0.532
AMD1
S-adenosylmethionine decarboxylase proenzyme.
      
 0.509
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
   
  
 0.481
MKRN2
Putative E3 ubiquitin-protein ligase makorin-2 isoform 1.
      
 0.468
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.