STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)    
Predicted Functional Partners:
IPPK
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.986
MINPP1
Multiple inositol polyphosphate phosphatase 1 isoform 1; Belongs to the histidine acid phosphatase family.
    
 0.964
INPP5K
Inositol polyphosphate-5-phosphatase K.
     
 0.946
ITPKC
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.920
PLCG1
Phosphoinositide phospholipase C.
     
 0.919
ITPKB
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.915
PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is t [...]
    
 0.912
PLCD3
Phosphoinositide phospholipase C.
    
 0.912
PLCE1
Phosphoinositide phospholipase C.
    
 0.912
PLCH1
Phosphoinositide phospholipase C.
    
 0.912
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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