STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100620620Histone H2A; Belongs to the histone H2A family. (113 aa)    
Predicted Functional Partners:
LOC100621389
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.723
KDM6B
Lysine demethylase 6B.
    
 0.721
LOC100152135
Histone H2B; Belongs to the histone H2B family.
   
 0.714
LOC100152878
Histone H2B; Belongs to the histone H2B family.
   
 0.714
I3LAJ9_PIG
Histone H2B; Belongs to the histone H2B family.
   
 0.714
HIST1H2BD
Histone H2B; Belongs to the histone H2B family.
   
 0.714
H2BU1
Histone H2B; Belongs to the histone H2B family.
   
 0.714
H2BC21
Histone H2B; Belongs to the histone H2B family.
   
 0.714
LOC100155267
Histone domain-containing protein; Belongs to the histone H2B family.
   
 0.713
H2BC11
Histone H2B; Belongs to the histone H2B family.
   
 0.713
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.