STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN13Calpain 13; Belongs to the peptidase C2 family. (668 aa)    
Predicted Functional Partners:
YPEL5
Protein yippee-like; Belongs to the yippee family.
   
  
 0.900
CAPNS1
Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
   
0.816
LCLAT1
PlsC domain-containing protein.
      
 0.796
CAST
Calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue; Belongs to the protease inhibitor I27 (calpastatin) family.
   
 
 0.711
YIPF6
Protein YIPF.
      
 0.652
ARHGAP4
Rho GTPase activating protein 4.
      
 0.647
ZSCAN12
Zinc finger and SCAN domain-containing protein 12 isoform X1.
   
 
 0.559
ZNF106
Zinc finger protein 106.
   
 
 0.551
TLK1
Tousled like kinase 1.
   
  
 0.537
TMPRSS11E
Transmembrane protease serine; Belongs to the peptidase S1 family.
   
 
 0.513
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.