STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)    
Predicted Functional Partners:
MAPK13
Mitogen-activated protein kinase.
    
 0.973
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
     
0.950
FOS
Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...]
     
0.948
MAPK12
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.938
MAPK14
Mitogen-activated protein kinase.
    
 0.938
MAPK8
Mitogen-activated protein kinase.
    
 0.932
MAPK10
Mitogen-activated protein kinase.
    
 0.932
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.779
NFATC3
Nuclear factor of activated T cells 3.
    
 
 0.718
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 
 0.703
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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