STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1977 aa)    
Predicted Functional Partners:
FAU
Ubiquitin-like protein FUBI.
   
 
 0.987
A0A287BBK4_PIG
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.987
A0A5G2QQZ4_PIG
Ubiquitin-like domain-containing protein.
   
 
 0.987
ELMO2
Engulfment and cell motility 2.
    
 0.937
RPL6
60S ribosomal protein L6; Component of the large ribosomal subunit.
   
 
 0.924
RAP1A
RAP1A, member of RAS oncogene family.
   
 0.923
RAP1B
RAP1B, member of RAS oncogene family.
   
 0.922
EEF1G
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 
 0.917
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]
  
 
 0.904
RPS7
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
   
 
 0.903
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.