STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRMPD3FERM and PDZ domain containing 3. (1760 aa)    
Predicted Functional Partners:
TMLHE
Trimethyllysine dioxygenase, mitochondrial isoform 1.
      
 0.736
FBXL20
F-box and leucine rich repeat protein 20.
   
  
 0.677
MROH2B
Maestro heat like repeat family member 2B.
   
  
 0.647
LIMA1
LIM domain and actin-binding protein 1; Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments (By similarity). Plays a role in cholesterol homeostasis. Influences plasma cholesterol levels through regulation of intestinal cholesterol absorption. May act as a scaffold protein by regulating NPC1L1 transportation, an essential protein for cholest [...]
      
 0.642
TMEM132E
Transmembrane protein 132E.
   
  
 0.638
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
      
 0.635
NXPE2
Uncharacterized protein.
      
 0.622
GPSM2
G-protein-signaling modulator 2 isoform X1.
    
 
 0.598
ASB11
Ankyrin repeat and SOCS box containing 11.
   
  
 0.595
CYBRD1
Cytochrome b reductase 1 isoform 1.
      
 0.575
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.