STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNRNPRHeterogeneous nuclear ribonucleoprotein R isoform X2. (633 aa)    
Predicted Functional Partners:
HNRNPK
Uncharacterized protein.
   
 0.900
HNRNPU
Heterogeneous nuclear ribonucleoprotein U isoform a.
   
 0.888
HNRNPC
Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.
   
 0.886
HNRNPL
Heterogeneous nuclear ribonucleoprotein L.
   
 0.874
SRSF1
Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]
   
 0.851
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.842
SRSF3
Serine and arginine rich splicing factor 3.
   
 0.788
HNRNPF
Heterogeneous nuclear ribonucleoprotein F.
   
 0.787
ILF2
Interleukin enhancer binding factor 2.
   
 
 0.784
HNRNPH1
Heterogeneous nuclear ribonucleoprotein H1.
   
 0.779
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.