NOS2 protein (Sus scrofa) - STRING interaction network

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NOS2

Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1195 aa)

Predicted Functional Partners:

ARG1

0.979

CALML5

0.972

ASS1

0.966

CALML4

0.964

ARG2

0.958

CALM3

0.954

ASL

0.952

AKT2

0.919

AKT1

0.919

AKT3

0.919

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSSSCP00000050721	ENSSSCP00000046221	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.902
AKT1	AKT3	ENSSSCP00000050721	ENSSSCP00000071150	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT1	NOS2	ENSSSCP00000050721	ENSSSCP00000058904	Non-specific serine/threonine protein kinase.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.919
AKT2	AKT1	ENSSSCP00000046221	ENSSSCP00000050721	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.902
AKT2	AKT3	ENSSSCP00000046221	ENSSSCP00000071150	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.903
AKT2	NOS2	ENSSSCP00000046221	ENSSSCP00000058904	Non-specific serine/threonine protein kinase.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.919
AKT3	AKT1	ENSSSCP00000071150	ENSSSCP00000050721	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT3	AKT2	ENSSSCP00000071150	ENSSSCP00000046221	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.903
AKT3	NOS2	ENSSSCP00000071150	ENSSSCP00000058904	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.919
ARG1	ARG2	ENSSSCP00000029011	ENSSSCP00000002491	Arginase-1.	Arginase.	0.910
ARG1	ASL	ENSSSCP00000029011	ENSSSCP00000008264	Arginase-1.	Argininosuccinate lyase isoform 1.	0.984
ARG1	ASS1	ENSSSCP00000029011	ENSSSCP00000040581	Arginase-1.	Argininosuccinate synthase 1.	0.713
ARG1	NOS2	ENSSSCP00000029011	ENSSSCP00000058904	Arginase-1.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.979
ARG2	ARG1	ENSSSCP00000002491	ENSSSCP00000029011	Arginase.	Arginase-1.	0.910
ARG2	ASL	ENSSSCP00000002491	ENSSSCP00000008264	Arginase.	Argininosuccinate lyase isoform 1.	0.978
ARG2	ASS1	ENSSSCP00000002491	ENSSSCP00000040581	Arginase.	Argininosuccinate synthase 1.	0.632
ARG2	NOS2	ENSSSCP00000002491	ENSSSCP00000058904	Arginase.	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...]	0.958
ASL	ARG1	ENSSSCP00000008264	ENSSSCP00000029011	Argininosuccinate lyase isoform 1.	Arginase-1.	0.984
ASL	ARG2	ENSSSCP00000008264	ENSSSCP00000002491	Argininosuccinate lyase isoform 1.	Arginase.	0.978
ASL	ASS1	ENSSSCP00000008264	ENSSSCP00000040581	Argininosuccinate lyase isoform 1.	Argininosuccinate synthase 1.	0.999

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