STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGFRL1Opioid growth factor receptor like 1. (464 aa)    
Predicted Functional Partners:
GSKIP
DUF727 domain-containing protein.
    
 
 0.570
APC2
Uncharacterized protein.
    
 
 0.524
APC
APC_basic domain-containing protein.
    
 
 0.524
FRAT1
Uncharacterized protein.
    
 
 0.514
FRAT2
FRAT regulator of WNT signaling pathway 2.
    
 
 0.514
FBXW11
F-box and WD repeat domain containing 11.
    
 
 0.501
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 
 0.501
UCK1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 
 0.469
JUP
Junction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...]
    
 
 0.469
CTNNB1
Catenin beta 1.
    
 
 0.469
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.