STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIG1Androgen induced 1. (315 aa)    
Predicted Functional Partners:
TESPA1
Thymocyte expressed, positive selection associated 1.
      
 0.834
RNF34
E3 ubiquitin-protein ligase RNF34 isoform 2.
      
 0.744
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
      
 0.689
TNK2
Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.676
ASCC3
Activating signal cointegrator 1 complex subunit 3.
      
 0.676
GPR39
G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity); Belongs to the G-protein coupled receptor 1 family.
      
 0.650
FTCD
Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool; In the N-terminal section; belongs to the formiminotransferase family.
   
  
 0.620
CPM
Carboxypeptidase M.
      
 0.610
PKP2
Plakophilin 2.
      
 0.548
METTL3
N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.
      
 0.530
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.