STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX3ALX homeobox 3. (362 aa)    
Predicted Functional Partners:
CDK14
Cyclin dependent kinase 14.
   
 
 0.591
GGT7
Gamma-glutamyltransferase 7.
      
 0.587
LHX4
LIM homeobox 4.
   
 
0.585
LHX3
LIM/homeobox protein Lhx3; Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity).
   
 
0.585
SMG6
SMG6 nonsense mediated mRNA decay factor.
      
 0.554
MFSD12
Major facilitator superfamily domain containing 12.
      
 0.553
PAX6
Paired box 6.
   
 
0.552
ZIC5
Zic family member 5.
   
 
 0.551
LDB1
LID domain-containing protein.
    
 
 0.542
LDB2
LIM domain binding 2.
    
 
 0.542
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.