STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTL10Actin like 10; Belongs to the actin family. (245 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 
 0.590
ACTL6A
Actin-like protein 6A isoform X1; Belongs to the actin family.
 
  
 
0.516
MYL1
Uncharacterized protein.
   
 
 0.512
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.502
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
0.502
DCTN2
Dynactin subunit 2.
   
 
 0.497
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 
 0.492
ACTR10
Actin-related protein 10; Belongs to the actin family.
   
 
0.474
ARID4A
AT-rich interaction domain 4A.
    
 
 0.459
ARID4B
AT-rich interaction domain 4B.
    
 
 0.459
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.