STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (670 aa)    
Predicted Functional Partners:
CALM3
Uncharacterized protein; Belongs to the calmodulin family.
   
 0.968
CALML5
Calmodulin like 5.
   
 0.963
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.963
CALML4
Uncharacterized protein.
    
 0.953
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
 0.951
GRM1
Glutamate metabotropic receptor 1.
   
 0.931
SLC6A3
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 0.927
MAPT
Microtubule-associated protein.
   
 0.926
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.925
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.923
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.