| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMH | CYP19A1 | ENSSSCP00000058593 | ENSSSCP00000046988 | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. | 0.925 |
| AMH | DAZL | ENSSSCP00000058593 | ENSSSCP00000073353 | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | Deleted in azoospermia-like protein. | 0.528 |
| AMH | DMRT1 | ENSSSCP00000058593 | ENSSSCP00000067348 | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | 0.876 |
| AMH | STRA8 | ENSSSCP00000058593 | ENSSSCP00000017519 | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | Stimulated by retinoic acid 8. | 0.410 |
| CYP19A1 | AMH | ENSSSCP00000046988 | ENSSSCP00000058593 | Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | 0.925 |
| CYP19A1 | DMRT1 | ENSSSCP00000046988 | ENSSSCP00000067348 | Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | 0.722 |
| DAZL | AMH | ENSSSCP00000073353 | ENSSSCP00000058593 | Deleted in azoospermia-like protein. | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | 0.528 |
| DAZL | DMRT1 | ENSSSCP00000073353 | ENSSSCP00000067348 | Deleted in azoospermia-like protein. | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | 0.673 |
| DAZL | REC8 | ENSSSCP00000073353 | ENSSSCP00000002187 | Deleted in azoospermia-like protein. | Meiotic recombination protein REC8 homolog. | 0.559 |
| DAZL | SPO11 | ENSSSCP00000073353 | ENSSSCP00000073803 | Deleted in azoospermia-like protein. | SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae). | 0.644 |
| DAZL | STRA8 | ENSSSCP00000073353 | ENSSSCP00000017519 | Deleted in azoospermia-like protein. | Stimulated by retinoic acid 8. | 0.866 |
| DAZL | TNP1 | ENSSSCP00000073353 | ENSSSCP00000017139 | Deleted in azoospermia-like protein. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.486 |
| DAZL | ZBTB16 | ENSSSCP00000073353 | ENSSSCP00000034371 | Deleted in azoospermia-like protein. | Zinc finger and BTB domain containing 16. | 0.726 |
| DMRT1 | AMH | ENSSSCP00000067348 | ENSSSCP00000058593 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). | 0.876 |
| DMRT1 | CYP19A1 | ENSSSCP00000067348 | ENSSSCP00000046988 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. | 0.722 |
| DMRT1 | DAZL | ENSSSCP00000067348 | ENSSSCP00000073353 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | Deleted in azoospermia-like protein. | 0.673 |
| DMRT1 | IP6K1 | ENSSSCP00000067348 | ENSSSCP00000012143 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.667 |
| DMRT1 | MSH4 | ENSSSCP00000067348 | ENSSSCP00000019449 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | MutS homolog 4. | 0.786 |
| DMRT1 | REC8 | ENSSSCP00000067348 | ENSSSCP00000002187 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | Meiotic recombination protein REC8 homolog. | 0.669 |
| DMRT1 | SPO11 | ENSSSCP00000067348 | ENSSSCP00000073803 | Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...] | SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae). | 0.716 |
