STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF4Zinc finger protein Eos isoform X1. (585 aa)    
Predicted Functional Partners:
FOXP3
Forkhead box protein P3 isoform a.
   
 
 0.727
IKZF3
IKAROS family zinc finger 3.
   
 
0.617
IL2RA
Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
   
  
 0.616
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2.
    
 
 0.590
LRRC32
Leucine rich repeat containing 32.
    
 
 0.589
CRBN
Cereblon.
    
 
 0.550
STX17
Syntaxin-17 isoform X1; Belongs to the syntaxin family.
      
 0.535
IKZF1
IKAROS family zinc finger 1.
   
  
0.523
LHFPL4
LHFPL tetraspan subfamily member 4 protein isoform X1.
      
 0.521
TESPA1
Thymocyte expressed, positive selection associated 1.
   
  
 0.499
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.