node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUB1B | PPP2CA | ENSSSCP00000022619 | ENSSSCP00000015208 | BUB1 N-terminal domain-containing protein. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.810 |
BUB1B | PPP2CB | ENSSSCP00000022619 | ENSSSCP00000072937 | BUB1 N-terminal domain-containing protein. | Serine/threonine-protein phosphatase. | 0.807 |
BUB1B | PPP2R1A | ENSSSCP00000022619 | ENSSSCP00000053789 | BUB1 N-terminal domain-containing protein. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.503 |
BUB1B | PPP2R1B | ENSSSCP00000022619 | ENSSSCP00000020079 | BUB1 N-terminal domain-containing protein. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.642 |
BUB1B | PPP2R5C | ENSSSCP00000022619 | ENSSSCP00000068274 | BUB1 N-terminal domain-containing protein. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.854 |
BUB1B | SGO1 | ENSSSCP00000022619 | ENSSSCP00000011956 | BUB1 N-terminal domain-containing protein. | Shugoshin 1. | 0.919 |
DRD2 | PPP2CA | ENSSSCP00000049999 | ENSSSCP00000015208 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.910 |
DRD2 | PPP2CB | ENSSSCP00000049999 | ENSSSCP00000072937 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase. | 0.909 |
DRD2 | PPP2R1A | ENSSSCP00000049999 | ENSSSCP00000053789 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.908 |
DRD2 | PPP2R1B | ENSSSCP00000049999 | ENSSSCP00000020079 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.904 |
DRD2 | PPP2R5C | ENSSSCP00000049999 | ENSSSCP00000068274 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.900 |
PPP1R1A | PPP2CA | ENSSSCP00000065737 | ENSSSCP00000015208 | Protein phosphatase 1 regulatory inhibitor subunit 1A. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.905 |
PPP1R1A | PPP2CB | ENSSSCP00000065737 | ENSSSCP00000072937 | Protein phosphatase 1 regulatory inhibitor subunit 1A. | Serine/threonine-protein phosphatase. | 0.905 |
PPP1R1A | PPP2R1A | ENSSSCP00000065737 | ENSSSCP00000053789 | Protein phosphatase 1 regulatory inhibitor subunit 1A. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.901 |
PPP1R1A | PPP2R1B | ENSSSCP00000065737 | ENSSSCP00000020079 | Protein phosphatase 1 regulatory inhibitor subunit 1A. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.901 |
PPP1R1A | PPP2R5C | ENSSSCP00000065737 | ENSSSCP00000068274 | Protein phosphatase 1 regulatory inhibitor subunit 1A. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.902 |
PPP2CA | BUB1B | ENSSSCP00000015208 | ENSSSCP00000022619 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | BUB1 N-terminal domain-containing protein. | 0.810 |
PPP2CA | DRD2 | ENSSSCP00000015208 | ENSSSCP00000049999 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | 0.910 |
PPP2CA | PPP1R1A | ENSSSCP00000015208 | ENSSSCP00000065737 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | Protein phosphatase 1 regulatory inhibitor subunit 1A. | 0.905 |
PPP2CA | PPP2CB | ENSSSCP00000015208 | ENSSSCP00000072937 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | Serine/threonine-protein phosphatase. | 0.907 |