ARHGAP33 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ARHGAP33

Rho GTPase activating protein 33. (1310 aa)

Predicted Functional Partners:

CDC42BPG

0.730

TMEFF2

0.670

CDC42BPB

0.656

BTNL9

0.603

CDC42

0.561

RHOQ

0.557

CEP250

0.555

ARHGEF7

0.521

SUCO

0.514

STBD1

0.504

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP33	ARHGEF7	ENSSSCP00000068596	ENSSSCP00000033427	Rho GTPase activating protein 33.	Rho guanine nucleotide exchange factor 7.	0.521
ARHGAP33	BTNL9	ENSSSCP00000068596	ENSSSCP00000024940	Rho GTPase activating protein 33.	Butyrophilin like 9.	0.603
ARHGAP33	CDC42	ENSSSCP00000068596	ENSSSCP00000029815	Rho GTPase activating protein 33.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.561
ARHGAP33	CDC42BPB	ENSSSCP00000068596	ENSSSCP00000035169	Rho GTPase activating protein 33.	Serine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.656
ARHGAP33	CDC42BPG	ENSSSCP00000068596	ENSSSCP00000013843	Rho GTPase activating protein 33.	CDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.730
ARHGAP33	CEP250	ENSSSCP00000068596	ENSSSCP00000019167	Rho GTPase activating protein 33.	Centrosome-associated protein CEP250 isoform X1.	0.555
ARHGAP33	RHOQ	ENSSSCP00000068596	ENSSSCP00000038926	Rho GTPase activating protein 33.	Rho-related GTP-binding protein RhoQ.	0.557
ARHGAP33	STBD1	ENSSSCP00000068596	ENSSSCP00000073856	Rho GTPase activating protein 33.	CBM20 domain-containing protein.	0.504
ARHGAP33	SUCO	ENSSSCP00000068596	ENSSSCP00000016418	Rho GTPase activating protein 33.	SUN domain containing ossification factor.	0.514
ARHGAP33	TMEFF2	ENSSSCP00000068596	ENSSSCP00000068509	Rho GTPase activating protein 33.	Transmembrane protein with EGF like and two follistatin like domains 2.	0.670
ARHGEF7	ARHGAP33	ENSSSCP00000033427	ENSSSCP00000068596	Rho guanine nucleotide exchange factor 7.	Rho GTPase activating protein 33.	0.521
ARHGEF7	CDC42	ENSSSCP00000033427	ENSSSCP00000029815	Rho guanine nucleotide exchange factor 7.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.968
ARHGEF7	CDC42BPB	ENSSSCP00000033427	ENSSSCP00000035169	Rho guanine nucleotide exchange factor 7.	Serine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.473
ARHGEF7	RHOQ	ENSSSCP00000033427	ENSSSCP00000038926	Rho guanine nucleotide exchange factor 7.	Rho-related GTP-binding protein RhoQ.	0.606
BTNL9	ARHGAP33	ENSSSCP00000024940	ENSSSCP00000068596	Butyrophilin like 9.	Rho GTPase activating protein 33.	0.603
BTNL9	CDC42BPG	ENSSSCP00000024940	ENSSSCP00000013843	Butyrophilin like 9.	CDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.618
BTNL9	CEP250	ENSSSCP00000024940	ENSSSCP00000019167	Butyrophilin like 9.	Centrosome-associated protein CEP250 isoform X1.	0.474
BTNL9	TMEFF2	ENSSSCP00000024940	ENSSSCP00000068509	Butyrophilin like 9.	Transmembrane protein with EGF like and two follistatin like domains 2.	0.609
CDC42	ARHGAP33	ENSSSCP00000029815	ENSSSCP00000068596	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rho GTPase activating protein 33.	0.561
CDC42	ARHGEF7	ENSSSCP00000029815	ENSSSCP00000033427	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rho guanine nucleotide exchange factor 7.	0.968