STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED1Sprouty related EVH1 domain containing 1. (445 aa)    
Predicted Functional Partners:
NF1
Neurofibromin 1.
    
 0.990
KRAS
KRAS proto-oncogene, GTPase.
   
 0.931
NRAS
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.
   
 0.827
SPRED2
Sprouty-related, EVH1 domain-containing protein 2 isoform a.
  
  
0.820
PIK3R2
Uncharacterized protein.
      
 0.814
HRAS
HRas proto-oncogene, GTPase.
   
 0.764
FGFRL1
Fibroblast growth factor receptor like 1.
     
 0.723
EGFL7
EGF like domain multiple 7.
    
 
 0.686
RASA1
RAS p21 protein activator 1.
     
 0.663
RASA2
RAS p21 protein activator 2.
     
 0.564
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.