STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FXNFrataxin. (264 aa)    
Predicted Functional Partners:
NFS1
Cysteine desulfurase, mitochondrial.
   
 0.998
LYRM4
Uncharacterized protein; Belongs to the complex I LYR family.
    
 0.991
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.988
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
    
 0.980
SCLY
Selenocysteine lyase.
   
 0.960
HMOX2
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
     
 0.928
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
     
 0.919
LOC100158001
Uncharacterized protein; Belongs to the multicopper oxidase family.
     
 0.919
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
     
 0.919
A0A5G2RE08_PIG
NifU_N domain-containing protein.
    
 
 0.907
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.