STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLA-DQA1SLA class II histocompatibility antigen, DQ haplotype D alpha chain. (255 aa)    
Predicted Functional Partners:
CD74
Thyroglobulin type-1 domain-containing protein.
   
 0.964
SLA-DRB1
Ig-like domain-containing protein.
   
0.904
HLA-DOB
HLA class II histocompatibility antigen, DO beta chain.
   
0.889
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
  
 
0.884
A0A286ZKB7_PIG
Ig-like domain-containing protein.
   
0.866
A0A287AAB9_PIG
Ig-like domain-containing protein.
   
0.866
SLA-DMB
Major histocompatibility complex, class II, DM beta.
   
0.801
SLA-DMA
Ig-like domain-containing protein; Belongs to the MHC class II family.
  
0.789
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 
 0.726
HCRT
Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity).
    
 
 0.703
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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