STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMDLEM domain-containing protein. (400 aa)    
Predicted Functional Partners:
LMNA
Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...]
    
 0.992
LMNB1
Lamin-B1 isoform 1; Belongs to the intermediate filament family.
    
 0.985
BANF1
Barrier to autointegration factor 1.
    
 0.968
LMNB2
Lamin B2; Belongs to the intermediate filament family.
    
 
 0.937
LBR
Lamin-B receptor.
     
 0.934
BANF2
Barrier to autointegration factor 2.
    
 
 0.902
A0A287ADF8_PIG
Uncharacterized protein.
    
 
 0.899
SUN1
Sad1 and UNC84 domain containing 1.
    
 
 0.871
SUN2
Sad1 and UNC84 domain containing 2.
    
 
 0.864
SYNE1
Uncharacterized protein.
    
 
 0.850
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.