STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSPO2Uncharacterized protein. (242 aa)    
Predicted Functional Partners:
LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4 isoform 1.
   
 0.995
LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1.
   
 0.989
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.963
ZNRF3
Zinc and ring finger 3.
   
 0.952
RNF43
RING-type domain-containing protein.
   
 0.848
KRT71
Keratin 71; Belongs to the intermediate filament family.
      
 0.653
FGF5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.605
WNT3A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 
 0.584
PPP1R1B
Protein phosphatase 1 regulatory subunit 1B; Inhibitor of protein-phosphatase 1.
      
 0.570
LRTM1
Leucine-rich repeat and transmembrane domain-containing protein 1 isoform 1.
   
  0.526
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.