node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRF5 | CDH5 | ENSSSCP00000001882 | ENSSSCP00000047033 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | 0.598 |
ADGRF5 | EMCN | ENSSSCP00000001882 | ENSSSCP00000072604 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. | Endomucin. | 0.662 |
ADGRF5 | ROBO4 | ENSSSCP00000001882 | ENSSSCP00000016125 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. | Roundabout guidance receptor 4. | 0.539 |
APLNR | CDH5 | ENSSSCP00000040764 | ENSSSCP00000047033 | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | 0.475 |
APLNR | EMCN | ENSSSCP00000040764 | ENSSSCP00000072604 | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | Endomucin. | 0.653 |
CDH5 | ADGRF5 | ENSSSCP00000047033 | ENSSSCP00000001882 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. | 0.598 |
CDH5 | APLNR | ENSSSCP00000047033 | ENSSSCP00000040764 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | 0.475 |
CDH5 | DLL4 | ENSSSCP00000047033 | ENSSSCP00000055160 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.662 |
CDH5 | EMCN | ENSSSCP00000047033 | ENSSSCP00000072604 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Endomucin. | 0.698 |
CDH5 | LYVE1 | ENSSSCP00000047033 | ENSSSCP00000027375 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X2. | 0.712 |
CDH5 | PDGFB | ENSSSCP00000047033 | ENSSSCP00000041857 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.487 |
CDH5 | PECAM1 | ENSSSCP00000047033 | ENSSSCP00000044878 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] | 0.999 |
CDH5 | ROBO4 | ENSSSCP00000047033 | ENSSSCP00000016125 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Roundabout guidance receptor 4. | 0.589 |
DLL4 | CDH5 | ENSSSCP00000055160 | ENSSSCP00000047033 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | 0.662 |
DLL4 | EMCN | ENSSSCP00000055160 | ENSSSCP00000072604 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Endomucin. | 0.738 |
DLL4 | LYVE1 | ENSSSCP00000055160 | ENSSSCP00000027375 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X2. | 0.573 |
DLL4 | PDGFB | ENSSSCP00000055160 | ENSSSCP00000041857 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.657 |
DLL4 | PECAM1 | ENSSSCP00000055160 | ENSSSCP00000044878 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] | 0.601 |
DLL4 | ROBO4 | ENSSSCP00000055160 | ENSSSCP00000016125 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | Roundabout guidance receptor 4. | 0.624 |
EMCN | ADGRF5 | ENSSSCP00000072604 | ENSSSCP00000001882 | Endomucin. | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. | 0.662 |