| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARRB1 | ARRB2 | ENSSSCP00000033134 | ENSSSCP00000060730 | Arrestin beta 1. | Arrestin beta 2. | 0.983 |
| ARRB1 | GRK2 | ENSSSCP00000033134 | ENSSSCP00000072808 | Arrestin beta 1. | G protein-coupled receptor kinase 2. | 0.985 |
| ARRB1 | GRK3 | ENSSSCP00000033134 | ENSSSCP00000063949 | Arrestin beta 1. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.982 |
| ARRB1 | OPRM1 | ENSSSCP00000033134 | ENSSSCP00000004401 | Arrestin beta 1. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.939 |
| ARRB1 | SMO | ENSSSCP00000033134 | ENSSSCP00000017553 | Arrestin beta 1. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.989 |
| ARRB2 | ARRB1 | ENSSSCP00000060730 | ENSSSCP00000033134 | Arrestin beta 2. | Arrestin beta 1. | 0.983 |
| ARRB2 | GRK2 | ENSSSCP00000060730 | ENSSSCP00000072808 | Arrestin beta 2. | G protein-coupled receptor kinase 2. | 0.985 |
| ARRB2 | GRK3 | ENSSSCP00000060730 | ENSSSCP00000063949 | Arrestin beta 2. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.982 |
| ARRB2 | OPRM1 | ENSSSCP00000060730 | ENSSSCP00000004401 | Arrestin beta 2. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.939 |
| ARRB2 | SMO | ENSSSCP00000060730 | ENSSSCP00000017553 | Arrestin beta 2. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.989 |
| CSNK1A1 | CSNK1D | ENSSSCP00000060731 | ENSSSCP00000072520 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | Casein kinase 1 delta. | 0.793 |
| CSNK1A1 | CSNK1G1 | ENSSSCP00000060731 | ENSSSCP00000051648 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. | 0.629 |
| CSNK1A1 | CSNK1G2 | ENSSSCP00000060731 | ENSSSCP00000059763 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | Casein kinase I isoform gamma-2; Belongs to the protein kinase superfamily. | 0.474 |
| CSNK1A1 | GRK2 | ENSSSCP00000060731 | ENSSSCP00000072808 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | G protein-coupled receptor kinase 2. | 0.924 |
| CSNK1A1 | GRK3 | ENSSSCP00000060731 | ENSSSCP00000063949 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.924 |
| CSNK1A1 | LOC100523244 | ENSSSCP00000060731 | ENSSSCP00000037265 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.793 |
| CSNK1A1 | SMO | ENSSSCP00000060731 | ENSSSCP00000017553 | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.983 |
| CSNK1D | CSNK1A1 | ENSSSCP00000072520 | ENSSSCP00000060731 | Casein kinase 1 delta. | Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. | 0.793 |
| CSNK1D | GRK2 | ENSSSCP00000072520 | ENSSSCP00000072808 | Casein kinase 1 delta. | G protein-coupled receptor kinase 2. | 0.919 |
| CSNK1D | GRK3 | ENSSSCP00000072520 | ENSSSCP00000063949 | Casein kinase 1 delta. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.919 |
