node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LAMTOR1 | LAMTOR2 | ENSSSCP00000073191 | ENSSSCP00000006926 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ragulator complex protein LAMTOR2 isoform 1. | 0.991 |
LAMTOR1 | LAMTOR3 | ENSSSCP00000073191 | ENSSSCP00000049016 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. | 0.998 |
LAMTOR1 | LAMTOR4 | ENSSSCP00000073191 | ENSSSCP00000069163 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. | 0.998 |
LAMTOR1 | LAMTOR5 | ENSSSCP00000073191 | ENSSSCP00000053110 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ragulator complex protein LAMTOR5; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assem [...] | 0.998 |
LAMTOR1 | RPTOR | ENSSSCP00000073191 | ENSSSCP00000020553 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Regulatory associated protein of MTOR complex 1. | 0.980 |
LAMTOR1 | RRAGA | ENSSSCP00000073191 | ENSSSCP00000005562 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras related GTP binding A. | 0.948 |
LAMTOR1 | RRAGB | ENSSSCP00000073191 | ENSSSCP00000024427 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding protein B long isoform. | 0.936 |
LAMTOR1 | RRAGC | ENSSSCP00000073191 | ENSSSCP00000003953 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras related GTP binding C. | 0.989 |
LAMTOR1 | RRAGD | ENSSSCP00000073191 | ENSSSCP00000032038 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding protein D. | 0.985 |
LAMTOR1 | SLC38A9 | ENSSSCP00000073191 | ENSSSCP00000044510 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Sodium-coupled neutral amino acid transporter 9 isoform X2. | 0.986 |
LAMTOR2 | LAMTOR1 | ENSSSCP00000006926 | ENSSSCP00000073191 | Ragulator complex protein LAMTOR2 isoform 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | 0.991 |
LAMTOR2 | LAMTOR3 | ENSSSCP00000006926 | ENSSSCP00000049016 | Ragulator complex protein LAMTOR2 isoform 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. | 0.998 |
LAMTOR2 | LAMTOR4 | ENSSSCP00000006926 | ENSSSCP00000069163 | Ragulator complex protein LAMTOR2 isoform 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. | 0.993 |
LAMTOR2 | LAMTOR5 | ENSSSCP00000006926 | ENSSSCP00000053110 | Ragulator complex protein LAMTOR2 isoform 1. | Ragulator complex protein LAMTOR5; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assem [...] | 0.990 |
LAMTOR2 | RPTOR | ENSSSCP00000006926 | ENSSSCP00000020553 | Ragulator complex protein LAMTOR2 isoform 1. | Regulatory associated protein of MTOR complex 1. | 0.864 |
LAMTOR2 | RRAGA | ENSSSCP00000006926 | ENSSSCP00000005562 | Ragulator complex protein LAMTOR2 isoform 1. | Ras related GTP binding A. | 0.909 |
LAMTOR2 | RRAGB | ENSSSCP00000006926 | ENSSSCP00000024427 | Ragulator complex protein LAMTOR2 isoform 1. | Ras-related GTP-binding protein B long isoform. | 0.876 |
LAMTOR2 | RRAGC | ENSSSCP00000006926 | ENSSSCP00000003953 | Ragulator complex protein LAMTOR2 isoform 1. | Ras related GTP binding C. | 0.943 |
LAMTOR2 | RRAGD | ENSSSCP00000006926 | ENSSSCP00000032038 | Ragulator complex protein LAMTOR2 isoform 1. | Ras-related GTP-binding protein D. | 0.868 |
LAMTOR2 | SLC38A9 | ENSSSCP00000006926 | ENSSSCP00000044510 | Ragulator complex protein LAMTOR2 isoform 1. | Sodium-coupled neutral amino acid transporter 9 isoform X2. | 0.953 |