Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACY1Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family. (437 aa)    
Predicted Functional Partners:
ARG2
Arginase.
  
 
 0.931
ARG1
Arginase-1.
  
 
 0.931
OTC
Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.914
ASS1
Argininosuccinate synthase 1.
  
 0.808
ABHD14A
Abhydrolase domain containing 14A.
 
 
 
 0.804
NUDT1
Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.
    
 
 0.756
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.738
PPME1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
   
 
 0.737
AGMAT
Agmatinase; Belongs to the arginase family.
  
 
 0.718
PMVK
Phosphomevalonate kinase.
   
  
 0.656
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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