node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRBN | ZBTB17 | ENSSSCP00000053546 | ENSSSCP00000074366 | Cereblon. | Zinc finger and BTB domain containing 17. | 0.615 |
DNAJC24 | DPH1 | ENSSSCP00000044614 | ENSSSCP00000023587 | DnaJ heat shock protein family (Hsp40) member C24. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 0.868 |
DNAJC24 | DPH2 | ENSSSCP00000044614 | ENSSSCP00000064691 | DnaJ heat shock protein family (Hsp40) member C24. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | 0.882 |
DNAJC24 | DPH5 | ENSSSCP00000044614 | ENSSSCP00000007313 | DnaJ heat shock protein family (Hsp40) member C24. | Diphthine methyl ester synthase isoform a. | 0.866 |
DNAJC24 | ZBTB17 | ENSSSCP00000044614 | ENSSSCP00000074366 | DnaJ heat shock protein family (Hsp40) member C24. | Zinc finger and BTB domain containing 17. | 0.778 |
DPH1 | DNAJC24 | ENSSSCP00000023587 | ENSSSCP00000044614 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | DnaJ heat shock protein family (Hsp40) member C24. | 0.868 |
DPH1 | DPH2 | ENSSSCP00000023587 | ENSSSCP00000064691 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | 0.981 |
DPH1 | DPH5 | ENSSSCP00000023587 | ENSSSCP00000007313 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Diphthine methyl ester synthase isoform a. | 0.988 |
DPH1 | ZBTB17 | ENSSSCP00000023587 | ENSSSCP00000074366 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Zinc finger and BTB domain containing 17. | 0.844 |
DPH2 | DNAJC24 | ENSSSCP00000064691 | ENSSSCP00000044614 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | DnaJ heat shock protein family (Hsp40) member C24. | 0.882 |
DPH2 | DPH1 | ENSSSCP00000064691 | ENSSSCP00000023587 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 0.981 |
DPH2 | DPH5 | ENSSSCP00000064691 | ENSSSCP00000007313 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | Diphthine methyl ester synthase isoform a. | 0.984 |
DPH2 | ZBTB17 | ENSSSCP00000064691 | ENSSSCP00000074366 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | Zinc finger and BTB domain containing 17. | 0.791 |
DPH5 | DNAJC24 | ENSSSCP00000007313 | ENSSSCP00000044614 | Diphthine methyl ester synthase isoform a. | DnaJ heat shock protein family (Hsp40) member C24. | 0.866 |
DPH5 | DPH1 | ENSSSCP00000007313 | ENSSSCP00000023587 | Diphthine methyl ester synthase isoform a. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 0.988 |
DPH5 | DPH2 | ENSSSCP00000007313 | ENSSSCP00000064691 | Diphthine methyl ester synthase isoform a. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. | 0.984 |
DPH5 | ZBTB17 | ENSSSCP00000007313 | ENSSSCP00000074366 | Diphthine methyl ester synthase isoform a. | Zinc finger and BTB domain containing 17. | 0.849 |
HUWE1 | MYC | ENSSSCP00000013120 | ENSSSCP00000074218 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.603 |
HUWE1 | ZBTB17 | ENSSSCP00000013120 | ENSSSCP00000074366 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. | Zinc finger and BTB domain containing 17. | 0.725 |
MAX | MYC | ENSSSCP00000049597 | ENSSSCP00000074218 | MYC associated factor X. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.994 |