STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AG1IA_09270S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (505 aa)    
Predicted Functional Partners:
AG1IA_02833
Adenine phosphoribosyltransferase.
 
 
 0.987
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.890
AG1IA_07256
Guanine deaminase.
    
 0.881
AG1IA_07867
Phosphorylase superfamily domain-containing protein.
    
 0.881
AG1IA_06162
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 
 0.868
AG1IA_07701
Cytoplasmic protein.
  
 
 0.856
AG1IA_01746
Nicotinate phosphoribosyltransferase.
    
 0.846
AG1IA_03193
Uncharacterized protein.
  
 
 0.843
AG1IA_00441
Uridine nucleosidase.
  
 0.843
AG1IA_03436
Nicotinate-nucleotide adenylyltransferase.
    
 0.842
Your Current Organism:
Rhizoctonia solani AG1IA
NCBI taxonomy Id: 983506
Other names: R. solani AG-1 IA, Rhizoctonia solani AG-1 IA, Rhizoctonia solani AG-1IA, Rhizoctonia solani AG-1IA SC, Rhizoctonia solani AG1 IA, Rhizoctonia solani AG1 IA SC, Rhizoctonia solani AG1-IA
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