AG1IA_07473 protein (Rhizoctonia solani AG1IA)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AG1IA_07473

Uncharacterized protein. (601 aa)

Predicted Functional Partners:

AG1IA_09281

0.708

AG1IA_09283

0.708

AG1IA_05994

0.708

AG1IA_05995

0.708

AG1IA_07598

0.655

AG1IA_10384

0.643

AG1IA_08583

0.636

AG1IA_08231

0.626

AG1IA_05240

0.626

AG1IA_04321

0.626

Your Current Organism:

Rhizoctonia solani AG1IA

NCBI taxonomy Id: 983506
Other names: R. solani AG-1 IA, Rhizoctonia solani AG-1 IA, Rhizoctonia solani AG-1IA, Rhizoctonia solani AG-1IA SC, Rhizoctonia solani AG1 IA, Rhizoctonia solani AG1 IA SC, Rhizoctonia solani AG1-IA

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AG1IA_04321	AG1IA_05240	L8WUH9	L8WRI1	Uncharacterized protein.	Armadillo/beta-catenin/plakoglobin.	0.794
AG1IA_04321	AG1IA_07473	L8WUH9	L8WJW8	Uncharacterized protein.	Uncharacterized protein.	0.626
AG1IA_04321	AG1IA_08231	L8WUH9	L8WHQ1	Uncharacterized protein.	Armadillo/beta-catenin/plakoglobin.	0.794
AG1IA_05240	AG1IA_04321	L8WRI1	L8WUH9	Armadillo/beta-catenin/plakoglobin.	Uncharacterized protein.	0.794
AG1IA_05240	AG1IA_07473	L8WRI1	L8WJW8	Armadillo/beta-catenin/plakoglobin.	Uncharacterized protein.	0.626
AG1IA_05240	AG1IA_08231	L8WRI1	L8WHQ1	Armadillo/beta-catenin/plakoglobin.	Armadillo/beta-catenin/plakoglobin.	0.775
AG1IA_05994	AG1IA_07473	L8WP91	L8WJW8	Peroxidase TAP.	Uncharacterized protein.	0.708
AG1IA_05995	AG1IA_07473	L8WPP9	L8WJW8	Uncharacterized protein.	Uncharacterized protein.	0.708
AG1IA_07473	AG1IA_04321	L8WJW8	L8WUH9	Uncharacterized protein.	Uncharacterized protein.	0.626
AG1IA_07473	AG1IA_05240	L8WJW8	L8WRI1	Uncharacterized protein.	Armadillo/beta-catenin/plakoglobin.	0.626
AG1IA_07473	AG1IA_05994	L8WJW8	L8WP91	Uncharacterized protein.	Peroxidase TAP.	0.708
AG1IA_07473	AG1IA_05995	L8WJW8	L8WPP9	Uncharacterized protein.	Uncharacterized protein.	0.708
AG1IA_07473	AG1IA_07598	L8WJW8	L8WNN4	Uncharacterized protein.	Spt3.	0.655
AG1IA_07473	AG1IA_08231	L8WJW8	L8WHQ1	Uncharacterized protein.	Armadillo/beta-catenin/plakoglobin.	0.626
AG1IA_07473	AG1IA_08583	L8WJW8	L8WHI4	Uncharacterized protein.	Protein binding protein.	0.636
AG1IA_07473	AG1IA_09281	L8WJW8	L8WES0	Uncharacterized protein.	Peroxidase TAP.	0.708
AG1IA_07473	AG1IA_09283	L8WJW8	L8WIQ1	Uncharacterized protein.	Uncharacterized protein.	0.708
AG1IA_07473	AG1IA_10384	L8WJW8	L8WBM9	Uncharacterized protein.	SH3 domain-containing protein.	0.643
AG1IA_07598	AG1IA_07473	L8WNN4	L8WJW8	Spt3.	Uncharacterized protein.	0.655
AG1IA_08231	AG1IA_04321	L8WHQ1	L8WUH9	Armadillo/beta-catenin/plakoglobin.	Uncharacterized protein.	0.794

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.809

expected number of edges:

22

PPI enrichment p-value:

0.00834

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0010467

Gene expression

10 of 175

1.05

1.27

1.82e-07

GO:0006351

Transcription, DNA-templated

4 of 27

1.46

1.14

0.0022

GO:0016070

RNA metabolic process

7 of 108

1.1

9.95e-05

GO:0006353

DNA-templated transcription, termination

2 of 4

1.99

0.81

0.0292

GO:0009059

Macromolecule biosynthetic process

7 of 187

0.87

0.68

0.0022

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003723

RNA binding

7 of 85

1.21

1.36

1.59e-05

GO:0003676

Nucleic acid binding

10 of 298

0.82

0.79

1.59e-05

GO:0003899

DNA-directed 5-3 RNA polymerase activity

2 of 5

1.89

0.77

0.0339

GO:0140098

Catalytic activity, acting on RNA

4 of 70

1.05

0.58

0.0321

GO:0140640

Catalytic activity, acting on a nucleic acid

5 of 138

0.85

0.49

0.0321

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:412

RNA degradation, and 3-5-exoribonuclease activity

3 of 6

1.99

1.67

0.00048

CL:53

Mixed, incl. Gene expression, and Nucleoside triphosphate biosynthetic process

10 of 187

1.02

1.21

1.60e-07

CL:62

Ribosomal protein, and Ribonucleoside triphosphate biosynthetic process

7 of 103

1.12

1.19

3.40e-05

CL:246

RNA polymerase

2 of 5

1.89

0.84

0.0247

CL:227

Mixed, incl. Ribosomal small subunit biogenesis, and PUA domain superfamily

2 of 7

1.75

0.73

0.0383

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ace03018

RNA degradation

4 of 10

1.89

2.09

3.58e-05

ace03020

RNA polymerase

2 of 4

1.99

0.92

0.0177

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0694

RNA-binding

6 of 63

1.27

1.34

6.85e-05

KW-0806

Transcription termination

2 of 3

2.12

0.88

0.0233

KW-0240

DNA-directed RNA polymerase

2 of 5

1.89

0.78

0.0325

KW-0548

Nucleotidyltransferase

3 of 34

1.24

0.65

0.0325

KW-0804

Transcription

4 of 78

1.0

0.56

0.0325

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003029

S1 domain

3 of 4

2.17

1.29

0.0037

IPR022967

RNA-binding domain, S1

3 of 5

2.07

1.27

0.0037

IPR012340

Nucleic acid-binding, OB-fold

4 of 29

1.43

1.0

0.0050

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00316

Ribosomal protein S1-like RNA-binding domain

3 of 5

2.07

1.67

0.00054

SM00322

K homology RNA-binding domain

2 of 5

1.89

0.84

0.0245

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