AG1IA_08811 protein (Rhizoctonia solani AG1IA)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AG1IA_08811

Uncharacterized protein. (408 aa)

Predicted Functional Partners:

AG1IA_04149

0.810

AG1IA_06192

0.742

AG1IA_08587

0.738

AG1IA_05948

0.738

AG1IA_03902

0.719

AG1IA_00997

0.713

AG1IA_01867

0.709

AG1IA_04067

0.708

AG1IA_05204

0.703

AG1IA_02470

0.703

Your Current Organism:

Rhizoctonia solani AG1IA

NCBI taxonomy Id: 983506
Other names: R. solani AG-1 IA, Rhizoctonia solani AG-1 IA, Rhizoctonia solani AG-1IA, Rhizoctonia solani AG-1IA SC, Rhizoctonia solani AG1 IA, Rhizoctonia solani AG1 IA SC, Rhizoctonia solani AG1-IA

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AG1IA_00997	AG1IA_01867	L8X3U2	L8X4R2	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin.	0.866
AG1IA_00997	AG1IA_02470	L8X3U2	L8X4D3	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.787
AG1IA_00997	AG1IA_03902	L8X3U2	L8X0D4	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	PTCB-BRCT domain-containing protein.	0.802
AG1IA_00997	AG1IA_04067	L8X3U2	L8WYQ4	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme family protein.	0.724
AG1IA_00997	AG1IA_04149	L8X3U2	L8WZQ2	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Cyclin-dependent protein kinase inhibitor.	0.753
AG1IA_00997	AG1IA_05204	L8X3U2	L8WRL8	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin ligase SCF complex subunit Cullin; Belongs to the cullin family.	0.787
AG1IA_00997	AG1IA_08811	L8X3U2	L8WK26	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.713
AG1IA_01867	AG1IA_00997	L8X4R2	L8X3U2	Ubiquitin.	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	0.866
AG1IA_01867	AG1IA_02470	L8X4R2	L8X4D3	Ubiquitin.	Uncharacterized protein.	0.871
AG1IA_01867	AG1IA_03902	L8X4R2	L8X0D4	Ubiquitin.	PTCB-BRCT domain-containing protein.	0.890
AG1IA_01867	AG1IA_04067	L8X4R2	L8WYQ4	Ubiquitin.	Ubiquitin conjugating enzyme family protein.	0.997
AG1IA_01867	AG1IA_04149	L8X4R2	L8WZQ2	Ubiquitin.	Cyclin-dependent protein kinase inhibitor.	0.781
AG1IA_01867	AG1IA_05204	L8X4R2	L8WRL8	Ubiquitin.	Ubiquitin ligase SCF complex subunit Cullin; Belongs to the cullin family.	0.871
AG1IA_01867	AG1IA_05948	L8X4R2	L8WT96	Ubiquitin.	Serglycin domain-containing protein.	0.402
AG1IA_01867	AG1IA_06192	L8X4R2	L8WTY2	Ubiquitin.	Serine/threonine-protein phosphatase.	0.579
AG1IA_01867	AG1IA_08587	L8X4R2	L8WKW8	Ubiquitin.	Multicopper oxidase domain-containing protein.	0.402
AG1IA_01867	AG1IA_08811	L8X4R2	L8WK26	Ubiquitin.	Uncharacterized protein.	0.709
AG1IA_02470	AG1IA_00997	L8X4D3	L8X3U2	Uncharacterized protein.	Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.	0.787
AG1IA_02470	AG1IA_01867	L8X4D3	L8X4R2	Uncharacterized protein.	Ubiquitin.	0.871
AG1IA_02470	AG1IA_04067	L8X4D3	L8WYQ4	Uncharacterized protein.	Ubiquitin conjugating enzyme family protein.	0.822

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.982

expected number of edges:

17

PPI enrichment p-value:

3.4e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0098609

Cell-cell adhesion

5 of 435

1.54

1.27

0.0013

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045294

Alpha-catenin binding

2 of 10

2.78

0.97

0.0174

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0014704

Intercalated disc

2 of 11

2.74

1.28

0.0048

GO:0005911

Cell-cell junction

4 of 317

1.58

1.15

0.0032

GO:0016342

Catenin complex

2 of 30

2.31

0.98

0.0154

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:37965

Cadherin-like superfamily, and Plakophilin/Delta catenin

5 of 97

2.2

3.1

5.32e-07

CL:38071

Mixed, incl. Limb expression 1, and Retina layer formation

3 of 11

2.92

2.95

3.94e-06

CL:6049

RHOU GTPase cycle, and Unconventional class IX myosin

3 of 14

2.81

2.83

6.30e-06

CL:37972

Cadherin-like superfamily, and Plakophilin/Delta catenin

4 of 85

2.16

2.61

5.75e-06

CL:38074

Limb expression 1, and Retina layer formation

2 of 5

3.09

1.87

0.00042

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04392

Hippo signaling pathway - multiple species

3 of 102

1.95

1.51

0.00098

map04520

Adherens junction

3 of 115

1.9

1.49

0.00098

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9013026

RHOB GTPase cycle

3 of 71

2.11

1.35

0.0027

MAP-8980692

RHOA GTPase cycle

3 of 178

1.71

0.86

0.0199

MAP-5218920

VEGFR2 mediated vascular permeability

2 of 35

2.24

0.79

0.0347

MAP-418990

Adherens junctions interactions

2 of 40

2.18

0.79

0.0347

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005911

Cell-cell junction

4 of 224

1.74

1.42

0.0010

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0518

Myosin

2 of 56

2.04

0.7

0.0499

KW-0106

Calcium

3 of 368

1.39

0.62

0.0499

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR046987

Unconventional class IX myosin

3 of 4

3.36

2.87

6.62e-06

IPR036023

Class IX myosin, motor domain

2 of 2

3.48

1.49

0.0021

IPR013284

Beta-catenin

2 of 3

3.31

1.47

0.0023

IPR020894

Cadherin conserved site

3 of 107

1.93

1.04

0.0100

IPR015919

Cadherin-like superfamily

3 of 122

1.87

0.99

0.0118

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00112

Cadherin repeats.

3 of 118

1.89

1.14

0.0057

SM00314

Ras association (RalGDS/AF-6) domain

2 of 30

2.31

0.94

0.0187

SM00185

Armadillo/beta-catenin-like repeats

2 of 32

2.28

0.94

0.0187

SM00242

Myosin. Large ATPases.

2 of 38

2.2

0.93

0.0187

SM00282

Laminin G domain

2 of 50

2.09

0.91

0.0199

(more ...)

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