AG1IA_02538 protein (Rhizoctonia solani AG1IA)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

AG1IA_02538

Non-specific serine/threonine protein kinase. (781 aa)

Predicted Functional Partners:

AG1IA_04271

0.973

AG1IA_07694

0.968

AG1IA_08958

0.944

AG1IA_07614

0.877

AG1IA_07613

0.877

AG1IA_09363

0.859

AG1IA_02572

0.852

AG1IA_05445

0.814

AG1IA_02278

0.800

AG1IA_01711

0.782

Your Current Organism:

Rhizoctonia solani AG1IA

NCBI taxonomy Id: 983506
Other names: R. solani AG-1 IA, Rhizoctonia solani AG-1 IA, Rhizoctonia solani AG-1IA, Rhizoctonia solani AG-1IA SC, Rhizoctonia solani AG1 IA, Rhizoctonia solani AG1 IA SC, Rhizoctonia solani AG1-IA

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AG1IA_01711	AG1IA_02538	L8X6J9	L8WZB5	Dynein light chain type 1 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.782
AG1IA_01711	AG1IA_04271	L8X6J9	L8WUL8	Dynein light chain type 1 domain-containing protein.	Snf1p protein kinase activator.	0.676
AG1IA_01711	AG1IA_07613	L8X6J9	L8WPV2	Dynein light chain type 1 domain-containing protein.	Uncharacterized protein.	0.676
AG1IA_01711	AG1IA_07614	L8X6J9	L8WJJ9	Dynein light chain type 1 domain-containing protein.	Uncharacterized protein.	0.676
AG1IA_01711	AG1IA_09363	L8X6J9	L8WIH6	Dynein light chain type 1 domain-containing protein.	Serine/threonine kinase.	0.773
AG1IA_02278	AG1IA_02538	L8X4Y8	L8WZB5	Acetyl-CoA carboxylase.	Non-specific serine/threonine protein kinase.	0.800
AG1IA_02278	AG1IA_04271	L8X4Y8	L8WUL8	Acetyl-CoA carboxylase.	Snf1p protein kinase activator.	0.675
AG1IA_02278	AG1IA_07613	L8X4Y8	L8WPV2	Acetyl-CoA carboxylase.	Uncharacterized protein.	0.675
AG1IA_02278	AG1IA_07614	L8X4Y8	L8WJJ9	Acetyl-CoA carboxylase.	Uncharacterized protein.	0.675
AG1IA_02278	AG1IA_07694	L8X4Y8	L8WPN2	Acetyl-CoA carboxylase.	AMPKBI domain-containing protein.	0.813
AG1IA_02538	AG1IA_01711	L8WZB5	L8X6J9	Non-specific serine/threonine protein kinase.	Dynein light chain type 1 domain-containing protein.	0.782
AG1IA_02538	AG1IA_02278	L8WZB5	L8X4Y8	Non-specific serine/threonine protein kinase.	Acetyl-CoA carboxylase.	0.800
AG1IA_02538	AG1IA_02572	L8WZB5	L8X305	Non-specific serine/threonine protein kinase.	Regulation of carbohydrate metabolism-related protein.	0.852
AG1IA_02538	AG1IA_04271	L8WZB5	L8WUL8	Non-specific serine/threonine protein kinase.	Snf1p protein kinase activator.	0.973
AG1IA_02538	AG1IA_05445	L8WZB5	L8WVZ0	Non-specific serine/threonine protein kinase.	Mip1 protein.	0.814
AG1IA_02538	AG1IA_07613	L8WZB5	L8WPV2	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.877
AG1IA_02538	AG1IA_07614	L8WZB5	L8WJJ9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.877
AG1IA_02538	AG1IA_07694	L8WZB5	L8WPN2	Non-specific serine/threonine protein kinase.	AMPKBI domain-containing protein.	0.968
AG1IA_02538	AG1IA_08958	L8WZB5	L8WKX5	Non-specific serine/threonine protein kinase.	Serine/threonine protein kinase Ssp1.	0.944
AG1IA_02538	AG1IA_09363	L8WZB5	L8WIH6	Non-specific serine/threonine protein kinase.	Serine/threonine kinase.	0.859

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.863

expected number of edges:

12

PPI enrichment p-value:

0.000464

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033108

Mitochondrial respiratory chain complex assembly

7 of 47

1.95

3.64

2.62e-09

GO:0033617

Mitochondrial cytochrome c oxidase assembly

5 of 29

2.01

2.69

2.00e-06

GO:0007005

Mitochondrion organization

9 of 274

1.29

1.84

5.45e-08

GO:0065003

Protein-containing complex assembly

8 of 488

0.99

0.95

0.00011

GO:0016043

Cellular component organization

10 of 1889

0.5

0.35

0.0153

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005507

Copper ion binding

4 of 22

2.04

1.91

0.00015

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005758

Mitochondrial intermembrane space

9 of 69

1.89

4.65

1.55e-13

GO:0005740

Mitochondrial envelope

10 of 466

1.11

1.46

1.23e-08

GO:0005743

Mitochondrial inner membrane

5 of 269

1.05

0.78

0.0042

GO:0031966

Mitochondrial membrane

6 of 422

0.93

0.72

0.0026

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:33498264

(2021) Regulation of COX Assembly and Function by Twin CX9C Proteins-Implications for Human Disease.

6 of 16

2.35

3.81

2.66e-08

PMID:18761382

(2009) Redox regulation of protein folding in the mitochondrial intermembrane space.

6 of 34

2.02

2.89

6.77e-07

PMID:28886682

(2017) Copper Acquisition and Utilization in Fungi.

6 of 36

2.0

2.86

6.77e-07

PMID:34557489

(2021) Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells.

6 of 47

1.88

2.56

2.01e-06

PMID:29495437

(2018) The Complexity of Mitochondrial Complex IV: An Update of Cytochrome c Oxidase Biogenesis in Plants.

5 of 25

2.08

2.44

1.11e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2974

Respiratory chain complex IV assembly, and Heme a metabolic process

9 of 18

2.48

8.1

5.75e-18

CL:2995

Mixed, incl. CHCH domain, and Cytochrome c oxidase biogenesis protein Cmc1 like

4 of 6

2.6

3.49

2.57e-07

CL:2977

Copper chaperone activity, and Cytochrome oxidase c subunit VIb

3 of 5

2.56

2.32

4.72e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005758

Mitochondrial intermembrane space

8 of 59

1.91

4.21

1.45e-11

GOCC:1902695

Metallochaperone complex

3 of 4

2.65

2.52

2.12e-05

GOCC:0005740

Mitochondrial envelope

9 of 368

1.17

1.52

1.20e-07

GOCC:0005739

Mitochondrion

10 of 851

0.85

0.87

2.70e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1015

Disulfide bond

8 of 97

1.69

3.31

1.73e-10

KW-0186

Copper

4 of 27

1.95

2.29

1.50e-05

KW-0496

Mitochondrion

10 of 807

0.87

0.91

1.36e-06

KW-0999

Mitochondrion inner membrane

4 of 213

1.05

0.6

0.0273

KW-0143

Chaperone

3 of 105

1.23

0.6

0.0448

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08583

Cytochrome c oxidase biogenesis protein Cmc1 like

2 of 2

2.78

1.06

0.0120

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013892

Cytochrome c oxidase biogenesis protein Cmc1-like

2 of 2

2.78

0.78

0.0390

IPR009069

Cysteine alpha-hairpin motif superfamily

2 of 3

2.6

0.78

0.0390

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