AG1IA_00861 protein (Rhizoctonia solani AG1IA)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

AG1IA_00861

Dynamitin domain-containing protein. (1208 aa)

Predicted Functional Partners:

AG1IA_07810

0.993

AG1IA_05580

0.991

AG1IA_01492

0.991

AG1IA_02332

0.988

AG1IA_06838

0.987

AG1IA_05920

0.983

AG1IA_02172

0.983

AG1IA_02173

0.983

AG1IA_01972

0.982

AG1IA_03705

0.971

Your Current Organism:

Rhizoctonia solani AG1IA

NCBI taxonomy Id: 983506
Other names: R. solani AG-1 IA, Rhizoctonia solani AG-1 IA, Rhizoctonia solani AG-1IA, Rhizoctonia solani AG-1IA SC, Rhizoctonia solani AG1 IA, Rhizoctonia solani AG1 IA SC, Rhizoctonia solani AG1-IA

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AG1IA_00861	AG1IA_01492	L8X4H5	L8X606	Dynamitin domain-containing protein.	Hexapep domain-containing protein.	0.991
AG1IA_00861	AG1IA_01972	L8X4H5	L8X0Y2	Dynamitin domain-containing protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.982
AG1IA_00861	AG1IA_02172	L8X4H5	L8X3Y4	Dynamitin domain-containing protein.	Dynactin.	0.983
AG1IA_00861	AG1IA_02173	L8X4H5	L8X466	Dynamitin domain-containing protein.	Dynactin.	0.983
AG1IA_00861	AG1IA_02332	L8X4H5	L8WZY9	Dynamitin domain-containing protein.	Cytoplasmic dynein intermediate chain.	0.988
AG1IA_00861	AG1IA_03705	L8X4H5	L8WWC4	Dynamitin domain-containing protein.	Uncharacterized protein.	0.971
AG1IA_00861	AG1IA_05580	L8X4H5	L8WQW3	Dynamitin domain-containing protein.	Actin domain-containing protein.	0.991
AG1IA_00861	AG1IA_05920	L8X4H5	L8WPW9	Dynamitin domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.983
AG1IA_00861	AG1IA_06838	L8X4H5	L8WRW1	Dynamitin domain-containing protein.	Dynactin, subunit p25.	0.987
AG1IA_00861	AG1IA_07810	L8X4H5	L8WJP9	Dynamitin domain-containing protein.	Dynactin p62 family domain-containing protein.	0.993
AG1IA_01492	AG1IA_00861	L8X606	L8X4H5	Hexapep domain-containing protein.	Dynamitin domain-containing protein.	0.991
AG1IA_01492	AG1IA_01972	L8X606	L8X0Y2	Hexapep domain-containing protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.958
AG1IA_01492	AG1IA_02172	L8X606	L8X3Y4	Hexapep domain-containing protein.	Dynactin.	0.967
AG1IA_01492	AG1IA_02173	L8X606	L8X466	Hexapep domain-containing protein.	Dynactin.	0.967
AG1IA_01492	AG1IA_02332	L8X606	L8WZY9	Hexapep domain-containing protein.	Cytoplasmic dynein intermediate chain.	0.928
AG1IA_01492	AG1IA_03705	L8X606	L8WWC4	Hexapep domain-containing protein.	Uncharacterized protein.	0.930
AG1IA_01492	AG1IA_05580	L8X606	L8WQW3	Hexapep domain-containing protein.	Actin domain-containing protein.	0.991
AG1IA_01492	AG1IA_05920	L8X606	L8WPW9	Hexapep domain-containing protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.980
AG1IA_01492	AG1IA_06838	L8X606	L8WRW1	Hexapep domain-containing protein.	Dynactin, subunit p25.	0.999
AG1IA_01492	AG1IA_07810	L8X606	L8WJP9	Hexapep domain-containing protein.	Dynactin p62 family domain-containing protein.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

45

average node degree:

8.18

avg. local clustering coefficient:

0.962

expected number of edges:

10

PPI enrichment p-value:

1.55e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031204

Post-translational protein targeting to membrane, translocation

4 of 6

3.28

4.69

2.97e-09

GO:0045047

Protein targeting to ER

5 of 28

2.7

4.55

2.49e-09

GO:0006612

Protein targeting to membrane

5 of 51

2.44

4.16

6.70e-09

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

4 of 17

2.82

3.98

4.00e-08

GO:0006616

SRP-dependent cotranslational protein targeting to membrane, translocation

3 of 5

3.23

3.36

8.22e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043022

Ribosome binding

4 of 61

2.27

2.52

1.25e-05

GO:0008320

Protein transmembrane transporter activity

2 of 13

2.64

1.13

0.0088

GO:0019838

Growth factor binding

2 of 18

2.5

1.12

0.0088

GO:0042562

Hormone binding

2 of 26

2.34

1.04

0.0119

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140534

Endoplasmic reticulum protein-containing complex

7 of 74

2.43

6.44

3.60e-14

GO:0071256

Translocon complex

4 of 4

3.45

5.6

7.00e-11

GO:0005789

Endoplasmic reticulum membrane

11 of 581

1.73

4.5

1.14e-16

GO:0005784

Sec61 translocon complex

3 of 3

3.45

4.0

5.84e-08

GO:0008250

Oligosaccharyltransferase complex

3 of 10

2.93

3.38

6.25e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:31634

Oligosaccharyltransferase complex, and Post-translational protein targeting to membrane, translocation

10 of 24

3.07

13.33

2.63e-26

CL:31636

Oligosaccharyltransferase complex, and Translocon-associated

8 of 18

3.1

10.68

7.22e-21

CL:31661

Mixed, incl. Sec61beta family, and Translocon-associated

5 of 5

3.45

6.95

2.28e-13

CL:31638

Oligosaccharyltransferase complex

3 of 11

2.89

5.12e-06

CL:31641

Oligosaccharyltransferase complex

2 of 5

3.05

1.68

0.00093

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04141

Protein processing in endoplasmic reticulum

10 of 303

1.97

5.9

1.62e-17

map03060

Protein export

4 of 39

2.46

3.66

8.41e-08

map04145

Phagosome

4 of 151

1.87

2.29

1.03e-05

map00510

N-Glycan biosynthesis

2 of 71

1.9

0.99

0.0120

map00513

Various types of N-glycan biosynthesis

2 of 80

1.85

0.98

0.0121

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

6 of 115

2.17

4.09

1.80e-09

MAP-9609523

Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

3 of 17

2.7

2.59

1.62e-05

MAP-72766

Translation

6 of 322

1.72

2.56

3.76e-07

MAP-9609507

Protein localization

3 of 210

1.61

0.87

0.0163

MAP-392499

Metabolism of proteins

6 of 2399

0.85

0.54

0.0181

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0071256

Translocon complex

5 of 6

3.37

6.9

2.69e-13

GOCC:0005789

Endoplasmic reticulum membrane

9 of 199

2.11

6.09

7.43e-16

GOCC:0005784

Sec61 translocon complex

4 of 5

3.35

5.38

1.69e-10

GOCC:0005783

Endoplasmic reticulum

10 of 354

1.9

5.24

5.63e-16

GOCC:0098796

Membrane protein complex

8 of 516

1.64

3.15

1.69e-10

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0256

Endoplasmic reticulum

4 of 61

2.27

2.93

1.65e-06

KW-0811

Translocation

2 of 13

2.64

1.72

0.00069

KW-1133

Transmembrane helix

10 of 6441

0.64

0.55

0.00019

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03911

Sec61beta family

2 of 2

3.45

1.62

0.0012

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030671

Protein transport Sec61-beta/Sbh

2 of 2

3.45

1.37

0.0035

IPR016482

Protein transport protein SecG/Sec61-beta/Sbh

2 of 2

3.45

1.37

0.0035

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