STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH00449.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (859 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.921
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.919
AEH00042.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.918
AEH00805.1
TIGRFAM: Pyruvate kinase; KEGG: gfo:GFO_3386 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family.
     
 0.918
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.918
AEH02298.1
PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: cao:Celal_2701 pyruvate phosphate dikinase pep/pyruvate-binding protein.
     
 0.918
mqo
PFAM: Malate:quinone-oxidoreductase; TIGRFAM: Malate:quinone-oxidoreductase; KEGG: zpr:ZPR_1178 malate:quinone oxidoreductase; HAMAP: Malate:quinone-oxidoreductase.
     
 0.918
AEH00047.1
TIGRFAM: Malate synthase A; KEGG: cat:CA2559_12308 malate synthase; PFAM: Malate synthase-like, core; Belongs to the malate synthase family.
     
 0.837
AEH00233.1
KEGG: cat:CA2559_05880 citrate synthase; TIGRFAM: Citrate synthase, type II; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
     
 0.837
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
  
 0.807
Your Current Organism:
Lacinutrix sp. 5H374
NCBI taxonomy Id: 983544
Other names: L. sp. 5H-3-7-4, Lacinutrix sp. 5H-3-7-4
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.