STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAV1Caveolin-1. (179 aa)    
Predicted Functional Partners:
CAV2
Caveolin-2.
  
0.999
SRC
Neuronal proto-oncogene tyrosine-protein kinase Src.
   
 0.985
FYN
Tyrosine-protein kinase Fyn.
   
 0.976
ITGB1
Integrin beta-1.
     
 0.972
NOS3
Nitric oxide synthase.
    
 0.968
DNM2
Dynamin-1.
   
 
 0.967
CAV3
Caveolin-3.
  
  
0.958
EGFR
Epidermal growth factor receptor.
   
 0.958
CALML5
Calmodulin.
   
 0.940
PRNP
Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...]
     
 0.936
Your Current Organism:
Camelus dromedarius
NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel
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