STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEPRLeptin receptor. (1161 aa)    
Predicted Functional Partners:
LEP
Leptin.
    
 0.996
JAK2
Tyrosine-protein kinase JAK2.
    
 0.993
SOCS3
Suppressor of cytokine signaling 3.
    
 0.982
POMC
Beta-endorphin; Beta-endorphin and Met-enkephalin are endogenous opiates; Belongs to the POMC family.
      
 0.917
AGRP
Agouti-related protein.
      
 0.915
NPY
Pro-neuropeptide Y.
      
 0.904
JAK3
Tyrosine-protein kinase JAK3.
    
 0.903
JAK1
Tyrosine-protein kinase JAK1.
    
 0.862
TYK2
Non-receptor tyrosine-protein kinase TYK2.
    
 0.862
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
     
 0.848
Your Current Organism:
Camelus dromedarius
NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.