Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DCS_06581DNA damage response protein WSS1. (404 aa)    
Predicted Functional Partners:
MMM1
Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]
    
 0.793
DCS_00720
Imidazoleglycerol-phosphate dehydratase.
   
 0.661
DCS_00801
Uncharacterized protein.
      
 0.619
DCS_06580
Amidase protein.
 
      0.617
DCS_06915
Putative manganese transport protein.
     
 0.604
DCS_07798
ZIP metal ion transporter.
     
 0.604
DCS_01309
Zinc/iron permease.
   
 0.585
DCS_06114
Alpha subunit of casein kinase; Belongs to the protein kinase superfamily.
    
 0.579
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
    
 0.579
DCS_05681
Mitochondrial import receptor subunit TOM40.
    
 
 0.547
Your Current Organism:
Drechmeria coniospora
NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora
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