Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCS_07918BAH domain-containing protein. (723 aa)    
Predicted Functional Partners:
DCS_07560
Cell division control protein; Belongs to the CDC6/cdc18 family.
   
 0.999
DCS_04334
DNA helicase; Belongs to the MCM family.
  
 0.999
DCS_04715
DNA helicase; Belongs to the MCM family.
   
 0.999
DCS_02718
Origin recognition complex subunit 2.
   
 0.999
DCS_06179
Origin recognition complex subunit Orc5.
   
 0.998
DCS_07381
Origin recognition complex subunit.
   
 0.998
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.998
DCS_00357
ORC4_C domain-containing protein.
   
 0.998
DCS_00791
DNA helicase; Belongs to the MCM family.
   
 0.998
DCS_02689
DNA helicase; Belongs to the MCM family.
   
 0.998
Your Current Organism:
Drechmeria coniospora
NCBI taxonomy Id: 98403
Other names: CBS 615.82, D. coniospora, Meria coniospora
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