STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGRA_0764Putative two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (421 aa)    
Predicted Functional Partners:
SGRA_0326
Histidine kinase; COG0642 Signal transduction histidine kinase.
 
 0.973
rpoN
COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.
 
  
 0.807
SGRA_0763
Hypothetical protein.
       0.773
cheA
COG0643 Chemotaxis protein histidine kinase and related kinases.
  
 
 0.715
pleC1
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
 0.629
cheB
Protein-glutamate methylesterase, two-component response regulator, chemotaxis; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 0.595
mcp
Methyl-accepting chemotaxis protein; COG2202 FOG: PAS/PAC domain.
  
 
 0.571
SGRA_0765
Hypothetical protein.
       0.533
degS
Multi-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain.
   
 
 0.491
SGRA_1857
Two component transcriptional regulator, LuxR family protein; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
  
 0.485
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.