STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGRA_3209COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (99 aa)    
Predicted Functional Partners:
rsbU
COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.986
SGRA_2608
Sigma factor regulation protein; COG2203 FOG: GAF domain.
 
   0.781
SGRA_3212
Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
   0.769
SGRA_3213
Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG0656 Aldo/keto reductases, related to diketogulonate reductase.
  
   0.769
SGRA_3217
Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
 
     0.587
SGRA_3210
Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein.
       0.584
SGRA_3211
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
       0.584
SGRA_3215
Hypothetical protein.
       0.583
SGRA_3208
Two component transcriptional regulator, LuxR family; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
    0.541
SGRA_3207
Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
    0.536
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.