STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pabBChorismate binding protein; COG0147 Anthranilate/para-aminobenzoate synthases component I. (429 aa)    
Predicted Functional Partners:
trpG
Glutamine amidotransferase of anthranilate synthase; COG0512 Anthranilate/para-aminobenzoate synthases component II.
 0.999
ilvE-2
Aminotransferase class IV; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
 
 
 0.969
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.960
aroA-2
Dahp synthetase i/kdsa; COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.
 
 
 0.910
SGRA_1745
N-(5'phosphoribosyl)anthranilate isomerase (PRAI).
  
  
 0.890
aroE
COG0169 Shikimate 5-dehydrogenase.
 
  
 0.787
SGRA_3648
Hypothetical protein; COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase.
       0.773
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
   
 0.723
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
   
 0.694
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.679
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.