STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALN75870.1Aureolysin; Extracellular zinc metalloprotease. (501 aa)    
Predicted Functional Partners:
ALN76337.1
Thermonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.701
ALN78089.1
Hemolysin III; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.555
mprF
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
   
 0.552
gap
Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
      
 0.521
ALN76637.1
Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
      
 0.521
scpA
Segregation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
      
 0.507
ALN78028.1
Cysteine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.507
ALN76073.1
Autolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.504
ALN75871.1
Phosphinothricin acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.503
ALN76743.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.489
Your Current Organism:
Staphylococcus agnetis
NCBI taxonomy Id: 985762
Other names: CCUG 59809, DSM 23656, S. agnetis, Staphylococcus agnetis Taponen et al. 2012, strain 6-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.