node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaE | dnaN | BTSPAZIEG_0158 | BTSPAZIEG_0003 | DNA polymerase III subunit alpha. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.997 |
dnaE | dnaX | BTSPAZIEG_0158 | BTSPAZIEG_0322 | DNA polymerase III subunit alpha. | DNA polymerase III subunit tau, isoform gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.998 |
dnaE | hisI | BTSPAZIEG_0158 | BTSPAZIEG_0075 | DNA polymerase III subunit alpha. | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.457 |
dnaE | holA | BTSPAZIEG_0158 | BTSPAZIEG_0297B | DNA polymerase III subunit alpha. | DNA polymerase III subunit delta, partial; 3'-end; 5'-end is gene BTSPAZIEG_0297A. | 0.997 |
dnaE | holB | BTSPAZIEG_0158 | BTSPAZIEG_0239 | DNA polymerase III subunit alpha. | DNA polymerase III subunit delta'. | 0.997 |
dnaE | ligA | BTSPAZIEG_0158 | BTSPAZIEG_0038 | DNA polymerase III subunit alpha. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.754 |
dnaE | pheA | BTSPAZIEG_0158 | BTSPAZIEG_0266 | DNA polymerase III subunit alpha. | P-protein; Slightly shortened 3'-end. | 0.485 |
dnaE | polA | BTSPAZIEG_0158 | BTSPAZIEG_0286 | DNA polymerase III subunit alpha. | DNA polymerase I, partial; Shortened 3'-end; Almost-intact 5'-3' exonuclease domain; lacking both 3'-5' exonuclease domain and Klenow fragment, this last one includes the region in charge of polymerase activity. | 0.907 |
dnaE | rep | BTSPAZIEG_0158 | BTSPAZIEG_0409 | DNA polymerase III subunit alpha. | ATP-dependent DNA helicase Rep, partial; Shortened 3'-end; Intact UvrD-helicase, UvrD_C domains; Has lost most of the C-terminal region that is highly variable among Rep and helicase II (UvrD). | 0.488 |
dnaN | dnaE | BTSPAZIEG_0003 | BTSPAZIEG_0158 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit alpha. | 0.997 |
dnaN | dnaX | BTSPAZIEG_0003 | BTSPAZIEG_0322 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit tau, isoform gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.998 |
dnaN | hisI | BTSPAZIEG_0003 | BTSPAZIEG_0075 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.544 |
dnaN | holA | BTSPAZIEG_0003 | BTSPAZIEG_0297B | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit delta, partial; 3'-end; 5'-end is gene BTSPAZIEG_0297A. | 0.997 |
dnaN | holB | BTSPAZIEG_0003 | BTSPAZIEG_0239 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit delta'. | 0.998 |
dnaN | ligA | BTSPAZIEG_0003 | BTSPAZIEG_0038 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.681 |
dnaN | pheA | BTSPAZIEG_0003 | BTSPAZIEG_0266 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | P-protein; Slightly shortened 3'-end. | 0.437 |
dnaN | polA | BTSPAZIEG_0003 | BTSPAZIEG_0286 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I, partial; Shortened 3'-end; Almost-intact 5'-3' exonuclease domain; lacking both 3'-5' exonuclease domain and Klenow fragment, this last one includes the region in charge of polymerase activity. | 0.999 |
dnaN | rep | BTSPAZIEG_0003 | BTSPAZIEG_0409 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase Rep, partial; Shortened 3'-end; Intact UvrD-helicase, UvrD_C domains; Has lost most of the C-terminal region that is highly variable among Rep and helicase II (UvrD). | 0.949 |
dnaX | dnaE | BTSPAZIEG_0322 | BTSPAZIEG_0158 | DNA polymerase III subunit tau, isoform gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III subunit alpha. | 0.998 |
dnaX | dnaN | BTSPAZIEG_0322 | BTSPAZIEG_0003 | DNA polymerase III subunit tau, isoform gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |