node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKO95221.1 | AKO95338.1 | MALG_00002 | MALG_00122 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.547 |
AKO95221.1 | AKO97072.1 | MALG_00002 | MALG_01903 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.691 |
AKO95221.1 | AKO98412.1 | MALG_00002 | MALG_03268 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III (xth). | 0.691 |
AKO95221.1 | mutM | MALG_00002 | MALG_03640 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | formamidopyrimidine-DNA glycosylase (fpg); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.469 |
AKO95221.1 | polA | MALG_00002 | MALG_03536 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |
AKO95338.1 | AKO95221.1 | MALG_00122 | MALG_00002 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.547 |
AKO95338.1 | AKO95339.1 | MALG_00122 | MALG_00123 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Hypothetical protein. | 0.658 |
AKO95338.1 | AKO95340.1 | MALG_00122 | MALG_00124 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Protein-disulfide isomerase. | 0.639 |
AKO95338.1 | AKO97072.1 | MALG_00122 | MALG_01903 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III. | 0.730 |
AKO95338.1 | AKO98412.1 | MALG_00122 | MALG_03268 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III (xth). | 0.730 |
AKO95338.1 | AKO98588.1 | MALG_00122 | MALG_03445 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | ADP-ribose pyrophosphatase. | 0.490 |
AKO95338.1 | AKO98721.1 | MALG_00122 | MALG_03578 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.605 |
AKO95338.1 | mutM | MALG_00122 | MALG_03640 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | formamidopyrimidine-DNA glycosylase (fpg); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.596 |
AKO95338.1 | polA | MALG_00122 | MALG_03536 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.591 |
AKO95338.1 | sfsA | MALG_00122 | MALG_03318 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Sugar fermentation stimulation protein; Belongs to the SfsA family. | 0.928 |
AKO95339.1 | AKO95338.1 | MALG_00123 | MALG_00122 | Hypothetical protein. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.658 |
AKO95339.1 | AKO95340.1 | MALG_00123 | MALG_00124 | Hypothetical protein. | Protein-disulfide isomerase. | 0.846 |
AKO95340.1 | AKO95338.1 | MALG_00124 | MALG_00122 | Protein-disulfide isomerase. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.639 |
AKO95340.1 | AKO95339.1 | MALG_00124 | MALG_00123 | Protein-disulfide isomerase. | Hypothetical protein. | 0.846 |
AKO95340.1 | polA | MALG_00124 | MALG_03536 | Protein-disulfide isomerase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.500 |